Product: Meddx_CRGT

MedDx 70 Multi-Cancer Genetic Tests

Recommended for

  • > 50 years old

  • With a personal or family history of mixed cancers affecting multiple organ systems.

  • Present an abnormal values on cancer markers through blood tests

  • Planning to retired

 

Key Checkup Items:

  • Breast and gynecologic

  • Genitourinary

HK$9,200.0
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1 Highlight Items

Cancer Screening

Highlight
  • Breast and gynecologic (breast, ovarian, uterine)
  • Genitourinary (renal/urinary tract, prostate)
2 Items

Cancer Screening

  • Brain/nervous system
  • Gastrointestinal (colorectal, gastric, pancreatic)
  • Endocrine (thyroid, paraganglioma/pheochromocytoma, parathyroid, pituitary)
  • Skin (melanoma, basal cell carcinoma)

70 Multi-Cancer Genetic Tests

  • 5 ml blood
  • Send to US laboratory
  • ~ 3-4 weeks for reporting
  • If the result is positive, you will be referred to a specialist consultation service once for free!

 

The Panel analyzes 70 genes associated with hereditary cancers across major organ systems, including:

  • breast and gynecologic (breast, ovarian, uterine)
  • gastrointestinal (colorectal, gastric, pancreatic)
  • endocrine (thyroid, paraganglioma/pheochromocytoma, parathyroid, pituitary)
  • genitourinary (renal/urinary tract, prostate)
  • skin (melanoma, basal cell carcinoma)
  • brain/nervous system

Test Panel List

Hereditary cancer risks and references (PDF here)

Education brochure (PDF here)

https://view.publitas.com/invitae/b134_invitae_hereditary_cancer_patient_guide/page/1

 

What is the test can tell you?

  • Positive Result = Higher chance or risk to have late stage cancer
  • Genetic Test can help to confirm the diagnosis by medical professionals and should help the treatment approach
  • The test is designed for heritable germline mutations,but not applied to somatic mutations in tumor tissue

 

The most common hereditary cancers

Breast cancer
BRCA1 and BRCA2 genes accounts for most cases in individuals with a strong family history or early onset diagnosis.

Ovarian
Lynch syndrome and hereditary breast and ovarian cancer syndrome (HBOC) are the most common causes of ovarian cancer.

Uterine
Lynch syndrome is the most common inherited cause of uterine cancer.

Colorectal
Hereditary colorectal cancer syndromes are generally divided into two types: Lynch syndrome and polyposis syndromes. Lynch syndrome, also called hereditary non-polyposis colon cancer (HNPCC), is caused by pathogenic variants in EPCAM, MLH1, MSH2, MSH6 and PMS2 and is the most common inherited cause of colorectal cancer.

Gastric
One cause of hereditary gastric cancer is a pathogenic variant in CDH1, which causes hereditary diffuse gastric cancer syndrome. However, there are a number of other genes in which pathogenic variants increase the risk of gastric tumors. Gastrointestinal stromal tumors (GISTs) are characterized as sarcomas and are rare tumors of the GI tract that account for 1%–3% of all gastric cancers.

Pancreatic
There are two main types of pancreatic cancer: cancer of the exonic pancreas (pancreatic adenocarcinoma), which accounts for 95% of pancreatic tumors, and pancreatic neuroendocrine tumors. Hereditary pancreatic cancer can be caused by BRCA2 and CDKN2A, as well as by several other genes.

Renal/urinary tract
Hereditary cancers of the kidneys and urinary tract are often characterized by earlier disease onset and multifocal or bilateral tumors. Hereditary urinary tract cancers may also be syndromic and associated with other non-urinary features.

Prostate
Approximately 5%–10% of cases are hereditary.

Melanoma
While the number of individuals who have an inherited risk of melanoma is unknown, it is thought to be low, and approximately 1%–2% of people with melanoma have two or more affected close relatives.

Thyroid

Medullary thyroid carcinoma (MTC) is a relatively uncommon type of thyroid malignancy and is more strongly associated with hereditary cancer syndromes.The familial form of MTC accounts for 20%–25% of cases and is usually a component of multiple endocrine neoplasia type 2 (MEN2), including subtypes MEN2A and MEN2B, or presents as familial MTC (FMTC) syndrome.

Hong Kong Allergy Test Center Terms and Conditions:

  • The plan will be valid for 3 months starting from the date of payment.
  • The Allergy Test report would be issued around 15-20 working days normally after the check-up.
  • Report should collect by email or in person at Meddx Centre for result.
  • Amendment or cancellation is not allowed once the payment is confirmed, and is not transferable nor refundable.
  • In case of disputes, the decision of Meddx and health.ESDlife shall be final.
  • All tests are not for the purpose of medical diagnosis or treatment.

 

Disclaimers:

  1. All health check/health screening services are not for the purpose of medical diagnostic or therapeutic purposes.   When there is any sign of symptom/disease in your health, please consult Doctor immediately for diagnosis and treatment. 
  2. The Merchant is the service provider of this Service/Product.  ESD Services Limited (“Health.ESDlife”) is not the service provider of this Service/Product.  Health.ESDlife is irresponsible to any loss, injury or law action caused by using this service/product.  Any claims and inquiries should be addressed to the respective Merchant.
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